19 Now we know that what things soever the law saith, it saith to them who are under the law: that every mouth may be stopped, and all the world may become guilty before God.
[AD 220] Tertullian on Romans 3:19
Whose grace, if not of that God from whom also came the law? Unless it be, forsooth, that the Creator intercalated His law for the mere purpose of producing some employment for the grace of a rival god, an enemy to Himself (I had almost said, a god unknown to Him), "that as sin had" in His own dispensation "reigned unto death, even so might grace reign through righteousness unto (eternal) life by Jesus Christ," His own antagonist! For this (I suppose it was, that) the law of the Creator had "concluded all under sin," and had brought in "all the world as guilty (before God)," and had "stopped every mouth," so that none could glory through it, in order that grace might be maintained to the glory of the Christ, not of the Creator, but of Marcion! I may here anticipate a remark about the substance of Christ, in the prospect of a question which will now turn up.

[AD 253] Origen of Alexandria on Romans 3:19
Here we must consider carefully what this law is that speaks to those who are under the law. By what it says to them it deprives them of every excuse, so that they can find no hiding place for their sins. It is this which stops every mouth and makes the whole world accountable to God. Now if we want to take this as referring to the law of Moses, which without doubt spoke only to those who had been circumcised from their mother’s womb and had learned what the law was, how is it possible that by that law, which applies to only one nation, every mouth should be stopped and the whole world should be held accountable to God? What have the other nations to do with that law, and why does it affect the entire world? And how is it that a knowledge of sin is said to have originated with the law of Moses, when there were many before his time who were well aware of their sins?From this it appears that the apostle Paul is not speaking here about the law of Moses but about the natural law which is written on the hearts of men.… This natural law speaks to all men who are under that law with the sole exception, it seems to me, of those children who are not yet able to distinguish good from evil.…
When Paul says “the whole world” he is not talking about trees and rocks and so on but about the rational animal, i.e., the human being. Anything which is not rational is excluded from consideration in this context.

[AD 384] Ambrosiaster on Romans 3:19
It is clear that the law censures those who did not believe first of all their leader Moses nor their ancestors the prophets, whom they killed, nor the apostles who were their kinsmen according to the flesh, whose blood they spilled. They were always ungodly and rebellious against God, so as to be condemned by the law whose authority they thought should be despised.Paul says this because with the Jews bound in sin the whole world has become subject to God. For there is no doubt that the pagans were immersed in sins and wickedness and that for that reason the whole world bowed before God in order to obtain forgiveness. The “whole world” means Jews and Gentiles, from whom believers are set apart. Therefore when Paul affirms that the Jews, who had received God’s law and to whom the promise had been given, were bound in sin, there is no doubt that all the Gentiles were guilty of death … for all have been found guilty and need the mercy of God, whether they be Jews or Gentiles.

[AD 407] John Chrysostom on Romans 3:19
This then is why, next to Isaiah, who confessedly aimed at them, he brought in David; that he might show that these things also belonged to the same subject. For what need was there, he means, that a prophet who was sent for your correction should accuse other people. For neither was the Law given to any else than you. And for what reason did he not say, we know that whatever things the prophet says, but whatever things the Law says? It is because Paul uses to call the whole Old Testament the Law. And in another place he says, "Do ye not hear the Law, that Abraham had two sons?" [Galatians 4:21-22] And here he calls the Psalm the Law when he says, "We know that whatever things the Law says, it says to them who are under the Law." Next he shows that neither are these things he said merely for accusation's sake, but that he may again be paving the way for faith. So close is the relationship of the Old Testament with the New, since even the accusations and reproofs were entirely with a view to this, that the door of faith might open brightly upon them that hear it. For since it was the principal bane of the Jews that they were so conceited with themselves (which thing he mentioned as he went on, "how that being ignorant of the righteousness of God, and going about to establish their own righteousness, they submitted not themselves to the righteousness of God") [Romans 10:3], the Law and the Prophet by being beforehand with them cast down their high thoughts, and laid low their conceit, that being brought to a consideration of their own sins, and having emptied out the whole of their unreasonableness, and seen themselves in danger of the last extremity, they might with much earnestness run unto Him Who offered them the remission of their sins, and accept grace through faith. And this it is then which St. Paul hints even here, when he says,

"Now we know that whatever things the Law says, it says to them who are under the Law, that every mouth may be stopped, and all the world may become guilty before God."

Here then he exhibits them as destitute of the boldness of speech which comes of works, and only using a parade of words and behaving in a barefaced way. And this is why he uses so literal an expression, saying, "that every mouth may be stopped," so pointing out the barefaced and almost uncontrollable pomposity of their language, and that their tongue was now curbed in the strictest sense. For as an unsupportable torrent, so had it been borne along. But the prophet stopped it. And when Paul says, "that every mouth may be stopped," what he means is, not that the reason of their sinning was that their mouth might be stopped, but that the reason of their being reproved was that they might not commit this very sin in ignorance. "And all the world may become guilty before God." He does not say the Jew, but the whole of mankind. For the phrase, "that every mouth may be stopped," is the language of a person hinting at them, although he has not stated it clearly, so as to prevent the language being too harsh. But the words "that all the world may become guilty before God," are spoken at once both of Jews and of Greeks. Now this is no slight thing with a view to take down their unreasonableness. Since even here they have no advantage over the Gentiles, but are alike given up as far as salvation is concerned. For he would be in strict propriety called a guilty person, who cannot help himself to any excuse, but needs the assistance of another: and such was the plight of all of us, in that we had lost the things pertaining to salvation.

[AD 407] John Chrysostom on Romans 3:19
Note that Paul was in the habit of referring to the entire Old Testament as “the law” … for here he calls a psalm “the law.”When he talks about every mouth being stopped, he does not mean that the purpose of their sinning was to shut them up but that the reason they were rebuked was that they might not sin in ignorance. Furthermore, it was not just the Jews he was referring to but the whole of mankind.

[AD 418] Pelagius on Romans 3:19
In case the Jews might claim that these verses of the psalm were spoken about the Gentiles, Paul indicates that what has been said in the law has been said to those who are under the law. Of course, it is a question as to who is meant by saying that the fool claims that there is no God. The Jews did not say this in words but in deeds, for they claimed to know God but denied it by their behavior. Paul is not talking to the Gentiles here, because he has already made similar statements about them.