Revelation 5:3

"And I saw an angel full of strength proclaiming with a loud voice, Who is worthy to open the book, and to loose the seals thereof? And no one was found worthy, neither in the earth nor under the earth, to open the book." Now to open the book is to overcome death for man.

[Daniel 12:4] "But Thou, O Daniel, shut up the words and seal the book, even to the time appointed. Many shall pass over, and knowledge shall be manifold." He who had revealed manifold truth to Daniel now signifies that the things he has said are matters of secrecy, and he orders him to roll up the scroll containing his words and set a seal upon the book, with the result that many shall read it and inquire as to its fulfilment in history, differing in their opinions because of its great obscurity. And as for the statement, "Many shall pass over" or "go through," this indicates that it will be read by many people. For it is a familiar expression to say: "I have gone through a book," or, "I have passed through an historical account." Indeed this is the idea which Isaiah also expressed in regard to the obscurity of his own book: "And the sayings of that book shall be like the words of a book that is sealed. And if they shall give it to an illiterate man, saying, 'Read it,' he will reply, 'I do not know how to read.' But if they give it to a man who does know how to read and say, 'Read the book,' he will reply, 'I cannot read it, because it is sealed up'" (Isaiah 29:11-12). Also in the Revelation of John, there is a book seen which is sealed with seven seals inside and outside. And when no one proves able to break its seals, John says, "I wept sore; and a voice came to me, saying, 'Weep not: behold the Lion of the tribe of Judah, the Root of David, has prevailed to open the book and break its seals'" (Revelation 5:1-5). But that book can be opened by one who has learned the mysteries of Scripture and understands its hidden truths, and its words which seem dark because of the greatness of the secrets they contain. He it is who can interpret the parables and transmute the letter which killeth into the spirit which quickeneth.

that is, neither angel, nor anyone living on earth, nor any of the dead, to contemplate the brightness of the grace of the New Testament.

He said, But no one in Heaven, on earth, or under the earth was able to open the little scroll. For neither an angel accomplished these things for us, as Isaiah says; "neither an elder nor an angel, but he himself saved them because he loved them," (Isa. 63:9) neither a living man, nor any of the dead. "A brother is not redeemed, a man shall not redeem himself," as it is written somewhere (Ps. 48:8). And what do I mean by saying to open the little scroll, when no one among men was able to look at it? For how could anyone filled with the mist of sin gaze upon the divine throne before which the little scroll was placed?

When it says that no one in heaven was found worthy, it indicates that [opening the scroll] exceeded the capacities of the angels. This was not because they were ignorant of the future mystery of the Lord's incarnation and work but because this was not to be completed through an angelic creature. For the Son of God, who through the assumption of true humanity was going to redeem humanity, wishes to fulfill all things through himself. Therefore Isaiah said, "Neither an angel nor a messenger but the Lord himself saved them." When it says that no one on the earth was worthy, it means that no one of the just remains perfect in this life, for in order to be re-created man requires the assistance of him who alone is Creator. And that no one could be found under the earth means that no one among the saints who had died was found worthy to open the scroll or even to see it. Here "to see" means "to comprehend," and therefore Paul says that he preaches the unsearchable riches of Christ to the Gentiles of which the Lord spoke, that is, the glory of the New Testament that was hidden in the law and that Christ reserved for his own presence. And so, no one was able to see this with an adequate sight, so that he might be able to effect it, since Christ had the power to fulfill it by his own dispensation. For [this glory] could only be foreseen by them, but it could not be effected.

or another sense; For a human to conquer death no one was found worthy to do this, neither among the angels of heaven, nor among humans on earth, nor among the souls of the saints in their rest, except Jesus Christ the Son of God alone.

Touching this point I dare not rashly define anything: for some have been of opinion that hell was in some place upon the earth; and others think that it is under the earth: but then this doubt ariseth, for if it be therefore called hell, or an infernal place, because it is below, then as the earth is distant from heaven, so likewise should hell be distant from the earth: for which cause, perhaps, the Prophet saith: Thou hast delivered my soul from the lower hell; so that the higher hell may seem to be upon the earth, and the lower under the earth: and with this opinion that sentence of John agreeth, who, when he had said, that he saw a book sealed with seven seals: and that none was found worthy, neither in heaven, nor in earth, nor under the earth, to open the book, and loose the seals thereof: he added forthwith: and I wept much: which book, notwithstanding, afterward he saith was opened by a lion of the tribe of Juda. By which book, what else can be meant but the holy scripture, which our Saviour alone did open: for being made man, by his death, resurrection, and ascension, he did reveal and make manifest all those mysteries which in that book were closed and shut up. And none in heaven, because not any Angel; none upon earth, because not man living in body; not any under the earth was found worthy: because neither the souls departed from their bodies could open unto us, beside our Lord himself, the secrets of that sacred book. Seeing, then, none under the earth is said to be found worthy to open that book, I see not what doth let, but that we should believe that hell is in the lower parts, under the earth.

This means that neither angels nor human beings, those in the flesh, nor the saints who had departed from the flesh are able to understand the knowledge of the divine judgments, except the lamb of God, by His presence releasing the obscurity of the things prophesied about him.

And no one was able in heaven or on earth, etc. Neither angel, nor any of the righteous even freed from the bond of the flesh, could reveal or investigate the mysteries of the divine law, nor look upon it, that is, to contemplate the splendor of the grace of the New Testament. Just as the children of Israel could not look upon the face of the giver of the Old Testament, which contains the New.

And no man was able, neither in heaven, that is no angel was able to, nor on earth, that is no human being, nor under the earth, that is no soul, to open the book, nor to look on it: for none of these was able to achieve the plan for the salvation of man. But, blessed John, how could no one look on the book, while you yourself say, "I saw a book in the right hand of God?" Perhaps you were neither in heaven, nor on earth, nor under the earth? Then, in order for it not to be contradictory, we should take look on to mean "comprehend." Indeed, who is able to comprehend how God can become incarnate without seed, how a man God can come out of the closed womb of a virgin, and how the Lord of glory can be crucified, when only the flesh dies?

QUESTION: And no man was able, neither in heaven, nor on earth, nor under the earth, to open the book. ANSWER: No angel nor any of the just, even freed from the bond of the flesh, was able to reveal or discover the mysteries of the divine law. — Nor to look on it. —That is, to contemplate the splendor of the grace of the New Testament, just like the children of Israel were unable to look at the face of the one who brought the Old Testament which contained the New. (5:4) THERE FOLLOWS: And I wept much. ANSWER: It means that he realized the common misery of mankind and felt sad. (5:5) THERE FOLLOWS: And one of the ancients said to me: Weep not; behold the lion of the tribe of Juda, the root of David, hath prevailed. ANSWER: He is forbidden to weep because the mystery that had long lain hidden had then already been fulfilled in Christ's Passion.

in heaven" refer to the angels, "on earth" to men living in the body, and "under the earth" to souls in hell.

And no man was able, neither in heaven: The angels. nor on earth: Humans. nor under the earth: The demons in whom the natural things remain intact. to open the book: No one can understand the divine mysteries, unless God, who first revealed them to the human Christ and Christ to John, reveals them.