"Unto You, O Lord, have I lift up my soul" [Psalm 25:1]: with spiritual longing have I lift up the soul, that was trodden down on the earth with carnal longings. "O my God, in You I trust, I shall not be ashamed" [Psalm 25:2]. O my God, from trusting in myself I was brought even to this weakness of the flesh; and I who on abandoning God wished to be as God, fearing death from the smallest insect, was in derision ashamed for my pride; now, therefore, "in You I trust, I shall not be ashamed."
From all earthly profit, from all the things of this world that seem good, raising my spirit, let me come to you, Lord; I have been lifted up, now not trusting in money, or house, or business, or military might or in my abilities, but I search while trusting in you, so that I will not be ashamed when I depart from this body.… I have lifted my spirit to you so that my spirit may dwell on good things.
This is the first psalm laid out by the Hebrew alphabet.… In the course of the whole book, there are two types of these psalms. The first is the type which is shown to contain the entire alphabet, as Psalms 111, 112 and 119.… The other type is the one that omits letters … such as the present psalm and Psalms 34, 37 and 145.… The alphabetic acrostics are not known as something unusual in the divine Scriptures, for Jeremiah also lamented the captivity of Jerusalem with a lament which repeated the alphabet four times. By doing this, he taught that the sacraments, which are the letters, also indicate for us the mysteries of heavenly matters.… In the entire psalm, the church prays in marvelous supplication, using the figure known as ethopoeia, that it might not appear in God’s view to be despicable to its enemies. In the first part, the church asks that it may understand the Lord’s instructions and ways. This section contains five letters of the alphabet which we noted. In the second part, the church requests the benefits that he has granted to the holy fathers from beginning of the world; in the third part, the church says that those who keep the Lord’s commands are worthy of eternal rewards; it attests that it remains constantly in the same desire; this is where the psalm contains the remaining nine letters.
[AD 430] Augustine of Hippo on Psalms 25:1-2