30 And thou shalt love the Lord thy God with all thy heart, and with all thy soul, and with all thy mind, and with all thy strength: this is the first commandment.
[AD 430] Augustine of Hippo on Mark 12:28-34
(de Con. Evan. ii. 73) Nor let it trouble us that Matthew says, that he who addressed this question to the Lord tempted Him; for it may be that though he came as a tempter, yet he was corrected by the answer of the Lord. Or at all events, we must not look upon the temptation as evil, and done with the intention of deceiving an enemy, but rather as the caution of a man who wished to try a thing unknown to him.

[AD 735] Bede on Mark 12:28-34
(ubi sup.) He shows when he says, this is greater than all sacrifices, that a grave question was often debated between the scribes and Pharisees, which was the first commandment, or the greatest of the Divine law; that is, some praised offerings and sacrifices, others preferred acts of faith and love, because many of the fathers before the law pleased God by that faith only, which works by love. This scribe shows that he was of the latter opinion. But it continues, And when Jesus saw that he answered discreetly, he said unto him, Thou art not far from the kingdom of God.

(ubi sup) But the reason why he was not far from the kingdom of God was, that he proved himself to be a favourer of that opinion, which is proper to the New Testament and to Gospel perfection.

(ubi sup.) For since they were confuted in argument, they ask Him no farther questions, but take Him without any disguise, and give Him up to the Roman power. From which we understand that the venom of envy may be overcome, but can hardly lie quiet.

[AD 1107] Theophylact of Ohrid on Mark 12:28-34
See how He has enumerated all the powers of the soul; for there is a 1living power in the soul, which He explains, when He says, With all thy soul, and to this belong anger and desire, all of which He will have us give to Divine love. There is also another power, which is called natural, to which belong nutriment and growth, and this also is all to be given to God, for which reason He says, With all thy heart. There is also another power, the rational, which He calls the mind, and that too is to be given whole to God.

He says that it is like, because these two commandments are harmonious one with the other, and mutually contain the other. For he who loves God, loves also His creature; but the chief of His creatures is man, wherefore he who loves God ought to love all men. But he who loves his neighbour, who so often offends him, ought much more to love Him, who is ever giving him benefits. And therefore on account of the connection between these commandments, He adds, There is none other commandment greater than these. It goes on: And the Scribe said unto him, Well, Master, thou hast said the truth: for there is one God, and there is none other but he: and to love him with all the heart, and with all the soul, and with all the understanding, and with all the strength, and to love his neighbour as himself, is more than all whole burnt offerings and sacrifices.

By which He shows that he was not perfect, for He did not say, Thou art within the kingdom of heaven, but, Thou art not far from the kingdom of God.

[AD 1274] Pseudo-Jerome on Mark 12:28-34
This question is only that which is a problem common to all skilled in the law, namely, that the commandments are differently set forth in Exodus, Leviticus, and Deuteronomy. Wherefore He brought forward not one but two commandments, by which, as by two paps rising on the breast of the bride, our infancy is nourished. And therefore there is added, And Jesus answered him, The first of all the commandments is, Hear, O Israel; the Lord thy God is one God. He mentions the first and greatest commandment of all; this is that to which each of us must give the first place in his heart, as the only foundation of piety, that is, the knowledge and confession of the Divine Unity, with the practice of good works, which is perfected in the love of God and our neighbour; wherefore there is added, Thou shalt love the Lord thy God with all thy heart, and with all thy mind, and with all thy soul, and with all thy strength: this is the first commandment.

Or else, he is not far who comes with knowledge; for ignorance is farther from the kingdom of God than knowledge; wherefore he says above to the Sadducees, Ye err, not knowing the Scriptures, or the power of God. It goes on: And no man after that durst ask him any questions.

[AD 1274] Glossa Ordinaria on Mark 12:28-34
(non occ.) That is, because they contradicted the Scriptures, and derogated from the power of God.

(non occ.) After that the Lord confuted the Pharisees, and the Sadducees, who tempted Him, it is here shown how He satisfied the Scribe who questioned Him; wherefore it is said, And one of the scribes came, and having heard them reasoning together, and perceiving that he had answered them well, asked him, Which is the first commandment of all?

(non occ.) The words which are added, And with all thy strength, may be referred to the bodily powers. It goes on: And the second is like, namely this, Thou shalt love thy neighbour as thyself.

[AD 1963] CS Lewis on Mark 12:29-31
Here is the paradox of Christianity. As practical imperatives for here and now the two great commandments have to be translated "Behave as if you loved God and man." For no man can love because he is told to. Yet obedience on this practical level is not really obedience at all. And if a man really loved God and man, once again this would hardly be obedience; for if he did, he would be unable to help it. Thus the command really says to us, "Ye must be born again." Till then, we have duty, morality, the Law. A schoolmaster, as St. Paul says, to bring us to Christ. We must expect no more of it than of a schoolmaster; we must allow it no less. I must say my prayers today whether I feel devout or not; but that is only as I must learn my grammar if I am ever to read the poets.

[AD 100] Didache on Mark 12:30-31
The way of life, then, is this: First, you shall love God who made you; second, your neighbour as yourself; and all things whatsoever you would should not occur to you, do not also do to another.

[AD 165] Justin Martyr on Mark 12:30
And that we ought to worship God alone, He thus persuaded us: "The greatest commandment is, Thou shalt worship the Lord thy God, and Him only shall thou serve, with all thy heart, and with all thy strength, the Lord God that made thee."

[AD 253] Origen of Alexandria on Mark 12:30
When you decide to keep the command of this precept and reject all other gods and lords and have no god or lord except the one God and Lord, you have declared war on all others without treaty. When, therefore, we come to the grace of baptism, renouncing all other gods and lords, we confess the only God, Father, Son and Holy Spirit.

[AD 379] Basil of Caesarea on Mark 12:30
It is not the privilege of any chance person to go forward to the perfection of love and to learn to know him who is truly beloved, but of him who has already “put off the old man, which is being corrupted through its deceptive lusts, and has put on the new man,” which is being renewed that it may be recognized as an image of the creator. Moreover, he who loves money and is aroused by the corruptible beauty of the body and esteems exceedingly this little glory here, since he has expended the power of loving on what is not proper, he is quite blind in regard to the contemplation of him who is truly beloved.

[AD 379] Basil of Caesarea on Mark 12:30
The expression, “with the whole,” admits of no division into parts. As much love as you shall have squandered on lower objects, that much will necessarily be lacking to you from the whole.

[AD 395] Gregory of Nyssa on Mark 12:30
Human life consists in a threefold unity. We are taught similarly by the apostle in what he says to the Ephesians, praying for them that the complete grace of their “body and soul and spirit” may be preserved at the coming of the Lord. We use the word “body,” for the nutritive part, the word for the vital, “soul,” and the word “spirit” for the intellective dimension. In just this way the Lord instructs the writer of the Gospel that he should set before every commandment that love to God which is exercised with all the heart and soul and mind. This single phrase embraces the human whole: the corporeal heart, the mind as the higher intellectual and mental nature, and the soul as their mediator.