16 Thy words were found, and I did eat them; and thy word was unto me the joy and rejoicing of mine heart: for I am called by thy name, O LORD God of hosts.
[AD 253] Origen of Alexandria on Jeremiah 15:15-16
The wonderful apostles who were insulted many times for the truth say, “I am content with weaknesses, with insults and hardships, persecutions and calamities for the sake of Christ.” I know that the basis of hardships is Christ when I am insulted if I know that I am insulted only for nothing other than for Christ, when I am in hardships, when I am abused if I know that the cause of abuse is none other than that I am a champion for truth and an ambassador for the Scriptures so that everything happens according to the Word of God. For this I am blasphemed. And thus let all of us, as far as our ability allows, strive for the prophetic life, for the apostolic life, not avoiding what is troublesome. For if the athlete avoids what is troublesome about the contest, the sweetness of the crown will never be his.

[AD 420] Jerome on Jeremiah 15:15-16
The saint does not look for rest but for tribulation. He knows “tribulation works out endurance, and endurance, tried virtue, and tried virtue, hope. And hope does not disappoint.” This is parallel to what Jeremiah says: “I have called on tribulation and misery, for your bitter word was to me joy and gladness.” In this world I desire nothing but tribulation that I may have happiness and repose in the next. That is why, he says, “I now bear with bitterness, that afterwards I may have all sweetness.” The people of the Lord coming out of Egypt came to Mara, which means “bitter,” and from Mara into Sinai, which means “temptation.” Again, Jeremiah says, “I sat alone because I was filled with bitterness.”

[AD 420] Jerome on Jeremiah 15:15-16
(Verse 15, 16.) You know, O Lord, remember me and visit me, and protect me from those who persecute me. Do not take me in your patience, know that I have endured reproach for you. Your words have been found and I have eaten them (or consume them from those who reject your words). And your word has become joy and gladness to my heart, for the name of the Lord God of hosts has been invoked upon me. What we have said, you know, is not found in the Septuagint. But blessed is that conscience which endures reproach for God. Hence he says: Your words were found by me, which you spoke with my mouth. And I ate them, that is, they were turned into food for me; or according to Symmachus: I received them, that they might be turned into joy for me, who had long been in reproach. Hence even the Babylonians confess that what Jeremiah had predicted was fulfilled: Or this is the meaning: I experienced distress: I endured the hardships of a persecuted people; but nevertheless, I rejoiced that I obeyed your commandments: and for the sake of your name, I endured hardships.