10 And gladness is taken away, and joy out of the plentiful field; and in the vineyards there shall be no singing, neither shall there be shouting: the treaders shall tread out no wine in their presses; I have made their vintage shouting to cease.
[AD 420] Jerome on Isaiah 16:9-10
(Verses 9, 10.) The scourges of the Lord have fallen upon the nations: they have reached even to Jazer. They have wandered in the desert: their branches have been left behind: they have crossed the sea. Therefore, I will weep over the vineyard of Sabama with weeping: I will drench you with my tears, O Heshbon and Eleale: for on your harvest and on your crop the voice of the treaders has fallen. Joy and gladness will be taken away from Carmel: there will be no rejoicing or jubilation in the vineyards: the one who used to tread the wine in the winepress will not tread it anymore: I have taken away the sound of the treaders. The suburban areas of Esebon, which we mentioned earlier, are deserted, and the vineyard of Sabama, which can be interpreted not only as a lofty elevation but also as some kind of conversion, because it seems that in the region of Moab, it wants to be partially converted to the service of the Lord. Therefore, the Apostles and apostolic men, servants of the Lord of nations, completely cut off the scourges and offshoots of this vine of Sabama, so that no other heresies would arise from other heresies, and a boundless multitude of the erring would not be made. And not only did the branches of Sabama fall, but they reached as far as Jazer, which is interpreted as their strength: that is, to the most powerful teachings of the heretics, and constructed with dialectic art, in which the strength of their error seemed to reside; and to such an extent was their sword brandished, that in the end they wandered in the wilderness and had no one to kill. And although those lashes were cut off, nevertheless, due to the fault of the rotten root, some branches remained. But the lords of the nations have passed over the sea, that is to say, the temptations of this world, of which we read in the psalm: Come into the depths of the sea, and the tempest shall swallow me up (Ps. 68: 3); and in another place: They that go down to the sea in ships, doing business in the great waters: these have seen the works of the Lord, and his wonders in the deep (Ps. 106: 23). Therefore, these have passed over the sea, in order to behold the works of the Lord and his wonders in the depths of temptations, while they are delivered from them. Therefore, the prophetic discourse laments the strength of the heretics, that is, Jazer and the vineyard of Sabama, which exalts itself against the knowledge of God. And I will intoxicate you with my tears, Esebon, the thoughts of the wise, and Eleale, who ascend to lofty heights. But why does he lament Jazer and intoxicate Esebon and Eleale with his tears? So that while he himself weeps, he may teach them to weep. For, he says, the voice of those who trample upon your harvest and your crop resounds. The vineyard of the Moabites is such because of the proximity of the place, just like the vineyard of the Sodomites, of which it is said: 'For their vine is of the vine of Sodom, and of the fields of Gomorrah' (Deut. 32:31). And in the seventy-seventh psalm, we read about the Egyptian vineyard that God struck with hail. The Moabite harvests also grow in the valleys called Raphaim: but its vintage is false, of which it is said above: 'The rods of those who lifted it up have been broken' (Num. 24:8). For they crush the most bitter grapes and trample on them with their feet, so that the venom of the dragon may not be squeezed out of them and all who drink may be killed. Also, the joy and exultation of the heretics will be taken away, which they used to enjoy before, so that after they have repented they may deserve to hear this: Blessed are those who mourn, for they will be comforted (Matthew 5:5). And what he added about Carmel means this: not that the heretics truly have Carmel, that is, the knowledge of spiritual circumcision; but that they boast falsely of having it. And when the vines have been cut down and the joy and exuberance have been taken away because of false knowledge of their name, then there will be no more of the former grape treaders, who used to tread the grapes before, and their voice will be silenced in eternal silence.

[AD 420] Jerome on Isaiah 16:10
(Verse 10) And joy and gladness shall be taken away from Carmel. It is the language of the Scriptures that always compares Mount Carmel, which overlooks Ptolemais and contains abundant forests, where Elijah prayed, to fertility and abundance, and thus signifies that all joy and fertility shall be taken away from once prosperous cities.

And in the vineyards there will be no rejoicing or jubilation. It is understood that the previous grape harvester, that is, the colonist of the Moabite province, will not be there. Finally, he immediately added:

Wine will not be pressed in the winepress by the one who was accustomed to tread it: I have taken away the voice of the treaders. The joyful grape harvester will by no means sing a song of celebration in the vineyard, but everywhere there will be the devastation of the enemy, and the cry of the victorious will arise.