Isaiah 15:6

(Verse 6) For the waters of Nemrim will be deserted. This town is on the Dead Sea, with salty waters, and even this itself is barren. Whether it alludes to the name, or whether it happened after the devastation, that even the waters turned bitter.

Because the grass has withered, the bud has failed, all the greenness has perished. Not as some think, truly because the waters of Nemrim were barren, all the grass has dried up, but Scripture speaks metaphorically. And the meaning is, in all of Moab the waters of Nemrim will be salty and bitter; just as no grass sprouts there, so the whole province will suffer from drought, that is, from Segor to Oronaim, from borders to borders. The same thing is said by Jeremiah: The waters of Nemrim will be very bad (Jerem. XLVIII, 34).

(Verse 6) And this will happen because the waters of Nemrim, that is, the teachings of heretics, which are compared to leopards and transgressors, will be deserted and brought to nothing. They are stubborn, whose variations and blemishes are not changed (Jeremiah XIII), and apostates, of whom we read in the Psalms, I have regarded all the sinners of the earth as transgressors (Psalm CXVIII, 119). Also, every plant and sprout, and everything that seemed green in their speech, withered. And they were visited by God according to the magnitude of their sins, so that those whom they had not felt through blessings, they would come to know through afflictions.

Third, the barrenness of their fields, for the waters, that is, the land of Moab will be so barren it will be like the territory around the town of Nemrim, which is by the sea, because its waters are salty and bitter; not indeed because of the waters, but by the judgment of God, the grass, already arisen, is withered away; the spring, as to what was sprouting; the greenness, of trees already arisen: he has turned rivers into a desert (Ps 106[107]:33).