18 And the LORD God said, It is not good that the man should be alone; I will make him an help meet for him.
[AD 50] Philo of Alexandria on Genesis 2:18
(17) Why God says, "It is not good for man to be alone; let us make him a help meet for him?" [Gen 2:18] By these words God intimates that there is to be a communion, not with all men, but with those who are willing to be assisted and in their turn to assist others, even though they may scarcely have any power to do so; since love consists not more in utility than in the harmonious concord of trustworthy and steadfast manners; so that every one who joins in a communion of love may be entitled to utter the expression of Pythagoras, "A friend is another I."

(18) Why, when God had already said, "Let us make a help for man," he creates beasts and cattle? [Gen 2:19] Perhaps some gluttons and insatiably greedy persons may say that God did this because beasts and flying things were, as it were, necessary food for man, and his meetest helper; for that the eating of meat assists the belly so as to conduce to the health and vigour of the body. But I should think that by reason of the evil implanted in them by nature animals of all kinds, whether terrestrial or flying in the air, were in this age hostile to and contrary to man; but that in the case of the first man, as one adorned with every imaginable virtue, they were, as it were, allies, and a reinforcement in war, and familiar friends, as being tame and domestic by nature, and this was the sole principle of their familiarity with man, for this it was fit that servants should dwell with their lord.

[AD 220] Tertullian on Genesis 2:18
[In goodness God] provided also a help meet for [the man] that there might not be anything in his lot that was not good. For God said that it is not good for the man to be alone. He knew full well what a blessing the gender of Mary would be to him and also to the church.

[AD 397] Ambrose of Milan on Genesis 2:18
Still another question arises, that concerning the saying of the Lord: 'It is not good for man to be alone.' [ Gen 2:18 ] Recognize the fact, first of all, that, when God created man from the slime of the earth, He did not add: 'God saw that it was good,' [ Gen 1:14 ] as He did in the case of each of His works. If He had said at that time that the creation of man was good, then the other statement that 'it is not good' would be a contradiction in terms, although He had said that the creation of what preceded the formation of man was good. That was the situation at the time of the creation of Adam. But, when He perceived that man and woman were joined together in creation, He did not treat each even then in a special manner, for He soon after states: 'God saw that all he had ever made was very good.' [ Gen 1:31 ] The meaning is clear. The creation of both man and woman is considered to be good.
From this question another problem arises. How did it happen that, when Adam alone was created, it was not said that it was good, but when a woman also was made, then are we to understand that everything was good? Whereas God in one case commended the whole of creation, as well as every creature in it (including man who is held to be a part of nature), a special reference to man did not then seem necessary. Wherefore, when Adam alone was created, an assertion that this work was good was not thought to be by any means a fitting climax to a satisfactory achievement. It was said, moreover, that it was not good for man to be alone. Yet we know that Adam did not commit sin before woman was created. However, after creation, she was the first to disobey the divine command and even allured her husband to sin. If, therefore, the woman is responsible for the sin, how then can her accession be considered a good? But, if you consider that the universe is in the care of God, then you will discover this fact, namely, that the Lord must have gained more pleasure for Himself in being responsible for all creation than condemnation from us for providing the basis for sin. Accordingly, the Lord declared that i[t] was not good for man to be alone, because the human race could not have been propagated from man alone. God preferred the existence of more than one whom He would be able to save than to have to confine this possibility to one man who was free from error. Inasmuch as He is the Author of both man and woman, He came into this world to redeem sinners. Finally, He did not permit Cain, a man accused of parricide, to perish before he brought forth sons. [ Gen 4:15-17 ] For the sake, therefore, of the successive generations of men it followed that woman had to be joined to man. Thus we must interpret the very words of God when He said the [NOTE: text wrong, should be that? -CA] it was not good for man to be alone. If the woman was to be the first one to sin, the fact that she was the one destined to bring forth redemption must not be excluded from the operations of Divine Providence. Although 'Adam was not deceived, the woman was deceived and was in sin.' [ 1 Tim 2:14 ] Yet woman, we are told, 'will be saved by childbearing,' 5 in the course of which she generated Christ.
Not without significance, too, is the fact that woman was made out of the rib of Adam. She was not made of the same earth with which he was formed, in order that we might realize that the physical nature of both man and woman is identical and that there was one source for the propagation of the human race. For that reason, neither was man created together with a woman, nor were two men and two women created at the beginning, but first a man and after that a woman. God willed it that human nature be established as one. Thus, from the very inception of the human stock He eliminated the possibility that many disparate natures should arise. He said: 'Let us make him a helper like himself.' [ Gen 2:18 ] We understand that to mean a helper in the generation of the human family-a really good helper. If we take the word 'helper' in a good sense, then the woman's cooperation turns out to be something of major import in the process of generation, just as the earth by receiving, confining, and fostering the seed causes it to grow and produce fruit in time. In that respect, therefore, woman is a good helper even through in an inferior position. We find examples of this in our own experience. We see how men in high and important offices often enlist the help of men who are below them in rank and esteem.
[AD 407] John Chrysostom on Genesis 2:18
The moment has arrived at long last, however, it would seem, for us to proceed with the theme of the reading. "The Lord God said," the text goes on, "'It is not good for the human being to be alone.'" [ Gen 2:18 ] See how once again it said in the same way as previously, "The Lord God," so that we should rivet the words on our minds and not think the fruit of our human reasoning to be superior to Sacred Scripture. "The Lord God said," it says, "'It is not good for the human being to be alone.'" Notice how the good God does not stop short, but adds kindness to kindness, and, in an abundance of riches, wants to clothe this rational being in every degree of esteem, and along with this esteem to regale him with a life of ease. The text says, remember, "The Lord God said, 'It is not good for the human being to be alone. Let us make him a helpmate like himself.'" Notice here again the expression, "'Let us make.'" In other words, just as he said at the beginning in the case of the formation of the human being, "'Let us make a human being in our image and likeness,'" so now, too, on the point of forming woman he employs the same expression, saying, "'Let us make.'" To whom does he address it? Not to any created power, but to the one begotten of him, Wonderful Counsellor, Figure of Authority, Prince of Peace, his only begotten Son. [ Isa 9:6 ] So that Adam may learn that the being in process of being formed is meant to enjoy equality of esteem with him, accordingly just as he said in the man's case, "'Let us make,'" so he now says also, "'Let us make him a helpmate like himself.'" Both expressions, helpmate and like himself have much significance.
[AD 407] John Chrysostom on Genesis 2:18
At that time God said, “Let us make for him a helper,” but in these times2 God says no such thing. Will he who has received the grace of the Spirit need any other help? How much need of assistance in the future has he who fills out the body of Christ? At that time he made man to the image of God, but now he has united him to God himself. At that time he commanded the man to rule over the fishes and the beasts. Now he has received our firstlings in heaven. Now he has given us the paradise to inhabit it. Now he has opened the gate of heaven to us. At that time man was formed on the sixth day, because the aeon had to be completed. Now he is formed on the first day and from the beginning and in the light.

[AD 735] Bede on Genesis 2:18
The Lord God also said: It is not good for man to be alone, let us make a helper suitable for him. And this speech of God is to be believed to have been made not by a corporeal voice emitted externally into the air, but on earth by the intention of the divine will, through which all things were created, ineffably, according to what we also taught above, where it is written: Let us make man in our image and likeness. But if someone asks for what purpose this helper needed to be made, let him hear the response of Saint Augustine, whose words we have very often included above, with his name silent. He said that nothing else likely occurs except for the sake of begetting children, just as help is for the seed in the earth, so that offspring may arise from both. For it was also said in the first condition of things: He made them male and female, and blessed them, saying: Be fruitful and multiply, and fill the earth and subdue it. This rationale for the condition and union of male and female and the blessing did not fail even after man's sin and punishment. For it is the same according to which the earth is now filled with men who dominate it. Although it is mentioned that they came together and begot after being expelled from paradise; nonetheless, I do not see what could have prevented them from having honorable marriages and an undefiled bed even in paradise, with God providing this to those living faithfully and justly and serving Him obediently and zealously, so that offspring would be begotten from their seed without any disturbing ardor of lust, without any labor and pain of giving birth, not that sons succeeded to dying parents, but so that, with those who begot remaining in some form of condition, and taking bodily vigor from the tree of life which was planted there, those who were begotten would be brought to the same condition, until the definite number was completed, if all lived justly and obediently, then that transformation would take place, so that without any death, the animal bodies converted to another quality, because they would serve the spirit ruling them at every nod, and living only by the spirit giving life without any sustenance of bodily food, they would be called spiritual. For if Enoch and Elijah, in Adam, did not die, carrying the progeny of death in the flesh, and are believed to return to this life to pay their due and to die, and now only live in another life where, before the resurrection of the flesh, before the animal body is transformed into a spiritual one, they do not decline by disease or old age, how much more justly and likely it would be granted to those first humans living without any sin of theirs or their parents, that having begotten children, they would yield to a better state from which, at the end of the age, with all the descendants of the saints, they would be transformed much more happily into the angelic form, not through the death of the flesh, but by the power of God.