Dates: c. 523 Summary: Philoxenus of Mabbug (d. 523), in his ascetic discourses, simply assumes the Sethite reading of Genesis 6. He treats the offending "sons of God" as "the children of Seth," who fell to "the lust of the belly" and so to fornication, and were on that account "rejected from the household of God." For Philoxenus the episode is a moral cautionary tale about gluttony giving rise to lust.
Now this is the first lust which conquered the world, and because of it the first transgression of the law took place. And in its train the children of Seth also came to fornication, so that they were rejected from the household of God thereby. For the lust of the belly is the captain of the host of the left side, and to it are fettered all the hosts of sin; and as captains of hosts go forth to war at the head of their companies against the enemy, even so also doth it, as the captain of the host of all wickedness, go forth to war against that which is good.
— 13 Ascetic Discourses, Discourse 11 -- On Abstinence, source. Philoxenus identifies the fallen "sons of God" with "the children of Seth" without argument, treating the Sethite reading as settled, and uses it to illustrate how gluttony leads to fornication.